Genetic Determinants of Poor Response to Treatment in Severe Asthma
نویسندگان
چکیده
منابع مشابه
Evaluation of Omeprazole in the Treatment of Moderate to Severe Persistent Asthma in Children
Background and Objective: Asthma is the most common chronic disease of childhood. The disease is caused by a temporary blockage of airflow due to chronic inflammation of the airways . One of the conditions that often occur with asthma and exacerbate disease, is gastroesophageal reflux. The aim of this study is to evaluate the role of acid suppressing therapy in patients with refractory asthma...
متن کاملRelation of measures of asthma severity and response to treatment to outcome in acute severe asthma.
BACKGROUND It would be helpful if patients with asthma who require admission to hospital for an acute attack could be identified. METHODS The relation between the severity of an attack of asthma as determined by admission assessment and the eventual outcome was studied in 52 asthmatic patients aged 14 to 44 years and admitted to an asthma emergency room. The patient's history, including medic...
متن کاملGenome-wide association study to identify genetic determinants of severe asthma.
BACKGROUND The genetic basis for developing asthma has been extensively studied. However, association studies to date have mostly focused on mild to moderate disease and genetic risk factors for severe asthma remain unclear. OBJECTIVE To identify common genetic variants affecting susceptibility to severe asthma. METHODS A genome-wide association study was undertaken in 933 European ancestry...
متن کاملevaluation of omeprazole in the treatment of moderate to severe persistent asthma in children
background and objective: asthma is the most common chronic disease of childhood. the disease is caused by a temporary blockage of airflow due to chronic inflammation of the airways . one of the conditions that often occur with asthma and exacerbate disease, is gastroesophageal reflux. the aim of this study is to evaluate the role of acid suppressing therapy in patients with refractory asthma. ...
متن کاملGenetic Determinants of Mitochondrial Response to Arsenic
We have used yeast Saccharomyces cerevisiae as a tool to identify the importance of mitochondrial processes involved in arsenic-induced carcinogenicity in humans. We screened 466 single-gene knockout strains of yeast S. cerevisiae known to be involved in biogenesis of mitochondria for sodium arsenite (AsIII) and sodium arsenate (AsV) sensitivity. We identified 72 arsenite-sensitive and 81 arsen...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2021
ISSN: 1422-0067
DOI: 10.3390/ijms22084251